Publications by authors named "A Cochet"
Article Synopsis
- PET/CT is a diagnostic imaging tool gaining traction for identifying large-vessel vasculitis, particularly giant cell arteritis (GCA).
- It effectively highlights inflammation in large arteries like the aorta, demonstrating its frequent involvement and the risk of serious complications like aneurysms.
- Despite its benefits, challenges and uncertainties remain regarding the overall effectiveness of PET/CT in diagnosing and monitoring GCA, which this review aims to address.
Article Synopsis
- This study assessed the effectiveness of F-fluorocholine (FCH) PET/CT for locating hyperfunctioning parathyroid glands in patients with primary hyperparathyroidism (PHPT) before surgery.
- The research involved 80 patients who underwent FCH PET/CT, comparing the imaging results with histological findings and postoperative outcomes to evaluate the method's diagnostic performance.
- Results showed that FCH PET/CT had a sensitivity of 88% and a positive predictive value of 91%, indicating it is a valuable tool for pre-surgical localization of problematic parathyroid tissue in PHPT patients.*
. We introduce a versatile methodology for the accurate modelling of PET imaging systems via Monte Carlo simulations, using the Geant4 application for tomographic emission (GATE) platform. Accurate Monte Carlo modelling involves the incorporation of a complete analytical signal processing chain, called the digitizer in GATE, to emulate the different count rates encountered in actual positron emission tomography (PET) systems.
View Article and Find Full Text PDFBackground: The aim of this study is to investigate the added value of combining tumour blood flow (BF) and metabolism parameters, including texture features, with clinical parameters to predict, at baseline, the pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in patients with newly diagnosed breast cancer (BC).
Methods: One hundred and twenty-eight BC patients underwent a F-FDG PET/CT before any treatment. Tumour BF and metabolism parameters were extracted from first-pass dynamic and delayed PET images, respectively.
Objectives: To evaluate the ability of FDG PET/CT, at diagnosis of giant cell arteritis (GCA) and during follow-up, to predict occurrence of relapse in large-vessel GCA (LV-GCA).
Methods: We conducted a retrospective study using the French Study Group for Large-Vessel Vasculitis (GEFA) network. Data from patients with LV-GCA diagnosed by PET/CT and who had PET/CT in the following year were collected.