Publications by authors named "A Clifton"
Children and adolescents (C&As) with congenital heart defects (CHDs) have decreased functional capacity and executive functioning (EF) due to brain abnormalities and decreased cerebral perfusion. Exercise may improve EF via increased cognitive demands and cerebral blood supply. The purpose of this review was to identify evidence describing the impact of physical activity (PA) interventions on EF in C&As with CHDs.
View Article and Find Full Text PDFImportance: Serious illness conversations (SICs) that elicit patients' values, goals, and care preferences reduce anxiety and depression and improve quality of life, but occur infrequently for patients with cancer. Behavioral economic implementation strategies (nudges) directed at clinicians and/or patients may increase SIC completion.
Objective: To test the independent and combined effects of clinician and patient nudges on SIC completion.
Article Synopsis
- - The study explores how social network analysis (SNA) can help identify alcohol use disorder (AUD) by examining the social relationships of individuals, particularly among university students.
- - Two studies compared individuals with AUD to matched drinkers without AUD using different SNA methods, finding that indicators of network alcohol severity were effective in distinguishing between the two groups.
- - The research suggests that social network indicators are promising tools for clinical assessments of AUD, with a simpler assessment method yielding results comparable to more detailed evaluations.
Hibernation in the thirteen-lined ground squirrel () takes place over 4-6 months and is characterized by multiday bouts of hypothermic torpor (5-7 °C core body temperature) that are regularly interrupted every 1-2 weeks by brief (12-24 h) normothermic active periods called interbout arousals. Our goal was to gain insight into the molecular mechanisms that underlie the hibernator's ability to preserve heart function and avoid the deleterious effects of skeletal muscle disuse atrophy over prolonged periods of inactivity, starvation, and near-freezing body temperatures. To achieve this goal, we performed organelle enrichment of heart and skeletal muscle at five seasonal time points followed by LC-MS-based label-free quantitative proteomics.
View Article and Find Full Text PDFBackground: Long COVID (LC) symptoms persist 12 weeks or more beyond the acute infection. To date, no standardised diagnostic or treatment pathways exist. However, a holistic approach has been recommended.
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