Publications by authors named "A Cleven"
Article Synopsis
- Juvenile xanthogranuloma (JXG) is a type of skin tumor mostly found in children, but some cases occur in other parts of the body, and their genetic causes are not fully understood.* -
- A study analyzed 16 children and 5 adults with extracutaneous JXG using advanced sequencing, finding that numerous genetic alterations, especially related to kinase fusions, were present in most children.* -
- The findings indicate that while surgery is common for treatment, some cases can regress on their own, and specific genetic alterations could help inform better treatment options in the future.*
Article Synopsis
- Odontogenic myxoma is a rare and aggressive benign tumor found in jaw areas, with no known molecular mechanisms or diagnostic markers currently.
- The study examined DNA methylation and copy number variations in 16 odontogenic myxomas to uncover potential new diagnostic signatures using advanced genomic techniques.
- Findings revealed a unique DNA methylation profile and recurrent chromosomal gains in the tumors, suggesting these genetic characteristics could aid in diagnosis, but further research is necessary to understand their underlying genetic causes.
Food deprivation can occur for different reasons. Fasting (<24 h duration) occurs to meet religious or well-being goals. Starvation (>1-day duration) occurs when there is intentional (hunger strike or treatment of a medical condition) or unintentional (anorexia nervosa, drought, epidemic famine, war, or natural disaster) food deprivation.
View Article and Find Full Text PDFPatients with gastro-intestinal stromal tumors (GISTs) undergoing tyrosine kinase inhibitor therapy are monitored with regular computed tomography (CT) scans, exposing patients to cumulative radiation. This exploratory study aimed to evaluate circulating tumor DNA (ctDNA) testing to monitor treatment response and compare changes in ctDNA levels with RECIST 1.1 and total tumor volume measurements.
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