Publications by authors named "A Claesson"
: Vancomycin is commonly used in the treatment of periprosthetic joint infection (PJI), and trough concentrations are measured to ascertain that they are within the therapeutic range. It has not been investigated what proportion of vancomycin concentrations during treatment of PJI patients is accurately within this range, how many dose adjustments are commonly needed, and which patient factors predispose towards aberrations from the desired range. : In this single-center cohort study, we investigated vancomycin trough concentrations in 108 patients with surgically treated PJI who received IV administered vancomycin treatment post-operatively.
View Article and Find Full Text PDFBackground: Despite declining over the past three decades, unintentional drownings still account for an estimated 236 000 annual deaths worldwide. Susceptibility persists amongst demographic groups and is influenced by sex, age, and socio-economic status, emphasizing the need for targeted interventions. Due to rapidly evolving population dynamics, particularly within Europe, there is a further responsibility to understand the impact of ethnicity on the risks of drowning to guide prevention.
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- The study investigates the survival rates of out-of-hospital cardiac arrest (OHCA) patients with shockable rhythms in relation to the number of defibrillations they received.
- It analyzed data from 10,549 patients in Sweden over a decade, finding that survival rates decreased significantly with each additional defibrillation.
- The results indicate that patients receiving more shocks had lower 30-day survival probabilities, suggesting that after a certain point, additional defibrillations may not be beneficial.
Article Synopsis
- Brain injury is the main cause of death after cardiac arrest and leads to severe disabilities in survivors, impacting patients, families, and society.
- This study aimed to investigate the relationship between neurologic recovery at hospital discharge and long-term survival, comparing patients with complete recovery to those with varying levels of disabilities.
- An analysis of 9,390 cardiac arrest survivors showed that 78.5% achieved complete recovery, and those with complete recovery had a significantly higher 5-year survival rate (73.8%) compared to those with moderate (64.7%) and severe disabilities (54.2%).