Publications by authors named "A Chuchalin"

Article Synopsis
  • Ferritin is an important protein that transports iron and serves as a marker for inflammation, oxidative stress, and aging processes in the body.
  • Human placental hydrolysates (HPHs) are being studied for their potential to protect the liver and counteract aging-related damage by regulating ferritin and iron metabolism.
  • Research suggests that blood levels of ferritin can indicate both the chronological and biological age of individuals, emphasizing its role in understanding aging.
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Background: Human placenta hydrolysates (HPH), the study of which was initiated by the scientific school of Vladimir P. Filatov, are currently being investigated using modern proteomic technologies. HPH is a promising tool for maintaining the function of mitochondria and regenerating tissues and organs with a high content of mitochondria (liver, heart muscle, skeletal muscles, etc.

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Article Synopsis
  • Mucosal immunity, particularly through secretory immunoglobulin A (sIgA), is crucial for preventing and influencing COVID-19 outcomes.
  • A study involving 69 moderate COVID-19 patients compared the effects of a bacteria-based immunostimulant, Immunovac VP4, with standard therapy on sIgA levels and disease progression.
  • Results showed that using Immunovac VP4 led to higher sIgA production, reduced C-reactive protein (CRP) levels, shorter fever duration, and decreased hospitalization compared to the control group.
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Article Synopsis
  • - Chronic obstructive pulmonary disease (COPD) has become a leading noncommunicable disease worldwide, contributing significantly to illness and death rates.
  • - Recent advancements in how we understand, diagnose, and treat COPD, including the use of effective drug combinations and non-medication methods, have changed the management of the condition.
  • - These updates reflect a new approach in clinical practice for diagnosing and treating COPD, emphasizing the importance of both medication and lifestyle changes.
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Article Synopsis
  • Post-COVID-19 syndrome (PS) affects 10-20% of COVID-19 patients, and the study explores the potential benefits of inhaling a combination of nitric oxide (iNO) and molecular hydrogen (iH) for those experiencing respiratory issues related to PS.
  • In a study involving 34 patients, those who received iNO/iH treatments showed significant improvements in symptoms like dyspnea, cough, and fatigue, along with enhanced scores in quality of life assessments and walking distance compared to the control group.
  • Results indicated a reduction in oxidative damage and improved blood flow, suggesting that combined inhalation therapy may be a safe and effective treatment option for alleviating respiratory manifestations in
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