Publications by authors named "A Chicos"
Inappropriate Therapy and Shock Rates Between the Subcutaneous and Transvenous Implantable Cardiac Defibrillator: A Secondary Analysis of the PRAETORIAN Trial.
Louise R A Olde Nordkamp Shari Pepplinkhuizen Abdul Ghani Lucas V A Boersma Juergen Kuschyk Alexandru B Chicos
Circ Arrhythm Electrophysiol
December 2024
Article Synopsis
- Inappropriate therapy (IAT) is a significant issue associated with implantable cardiac defibrillator (ICD) therapy, particularly highlighted in early subcutaneous ICD (S-ICD) studies which showed high rates of inappropriate shocks (IAS).
- The PRAETORIAN trial, an international study with 849 patients, found no major differences in IAT and IAS rates between S-ICD and transvenous ICD (TV-ICD) groups, as both groups had similar cumulative incidences.
- Key predictors for IAT varied between the two groups, with TV-ICD patients experiencing IAT mainly from supraventricular tachycardias, while S-ICD patients faced issues from cardiac oversensing
Article Synopsis
- The S-ICD was created to eliminate lead-related issues found in the TV-ICD, as it is an external device that sits under the skin rather than using leads inside the body.
- This analysis comes from the PRAETORIAN trial, where patients were randomly assigned to either S-ICD or TV-ICD and assessed for quality of life through various questionnaires at different stages.
- Results showed no significant differences in physical and mental well-being between the groups, but patients who experienced a shock recently reported lower social functioning and emotional health compared to those who did not.
Rates of and Indications for Subcutaneous ICD Extraction: A Multihospital Healthcare System Analysis.
J Cardiovasc Electrophysiol
January 2025
Article Synopsis
- The study investigates the rates and reasons for the removal of subcutaneous implantable cardioverter defibrillators (S-ICDs) among patients who've had them implanted.
- Out of 372 patients studied over a median follow-up of 4.4 years, 5.9% required extraction, mainly due to bradycardia pacing needs, infections, and inappropriate shocks.
- Factors such as a history of smoking and a higher body mass index were linked to an increased likelihood of S-ICD extraction, indicating the importance of careful patient selection for the device.
Article Synopsis
- The study compared high-density (HD) mapping to non-HD mapping in atrial flutter ablation to assess outcomes and healthcare utilization.
- Results showed that HD mapping led to a higher rate of successful circuit identification and a greater overall procedure success rate.
- Additionally, patients who had HD mapping experienced fewer emergency department visits and hospitalizations related to atrial flutter within a year post-procedure.
Background: The use of intravenous (IV) sotalol loading following recent U.S. Food and Drug Administration (FDA) approval of a 1-day loading protocol has reduced the obligatory 3-day hospital stay for sotalol initiation when given orally.
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