Publications by authors named "A Chianese"
Article Synopsis
- This study presents a new method for activating the N-H bond in ammonia at room temperature using a specific diphosphine compound, leading to a zwitterionic product.
- Unlike traditional phosphorus-based methods that require structural constraints, this process relies on the teamwork of electron-rich phosphine centers and an electron-accepting carborane cluster.
- The research highlights a unique, metal-free approach to ammonia oxidation through triple hydrogen atom abstraction, demonstrating that activation can occur in the presence of air and water without the need for metal catalysts.
In this article, we describe a detailed experimental and computational study of the activation mechanism for a highly active pincer ruthenium(0) precatalyst for the hydrogenation of polar organic compounds. The precatalyst activates by reaction with 2 equiv of hydrogen, resulting in a net oxidative addition to ruthenium and hydrogenation of an imine functional group on the supporting ligand. The kinetics of precatalyst hydrogenation were measured by UV-visible spectroscopy under catalytically relevant conditions (10-39 bar hydrogen, 298 K).
View Article and Find Full Text PDFFood plant diversity in bioactive compounds makes them an exploitable resource in the search for effective natural products to prevent or treat viral infections. Therefore, in the framework aimed at studying the antiviral properties of extractive mixtures from fruits (and their waste) grown in the Campania Region (Italy), jujube drupes ( Mill.) were our focus.
View Article and Find Full Text PDF() is a plant widely used for its beneficial properties both in medical and non-medical fields. Because they produce bioactive metabolites, plants are a major resource for drug discovery. In this study, two different cultivars of leaves of (Salento and Barletta) were obtained by maceration or microwave-assisted extraction (MAE).
View Article and Find Full Text PDFCandida albicans is an opportunistic yeast accounting for about 50-90 % of all cases of candidiasis in humans, ranging from superficial to systemic potentially life-threatening infections. The presence of several virulence factors, including biofilm, hyphal transition, and proteolytic enzymes production, worsens the fungal infections burden on healthcare system resources. Hence, developing new bioactive compounds with antifungal activity is a pressing urgence for the scientific community.
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