Publications by authors named "A Chernosky"
Purpose: To determine whether total corneal incision enlargement after implantation of an intraocular lens with a new preloaded delivery system is comparable to a standard-of-care manual delivery system using an in vitro human cadaver eye model, despite having a smaller initial incision size.
Methods: Human cadaver phakic whole eye globes were used for these studies (n = 16 per group). Each pair of eyes was randomly assigned to a new preloaded delivery system (UltraSert) or a manual delivery system (MONARCH III D).
In vitro delivery performance assessment of a new preloaded intraocular lens delivery system.
J Cataract Refract Surg
December 2016
Article Synopsis
- The study aimed to evaluate the delivery performance of a new preloaded intraocular lens system (Ultrasert) against two other preloaded systems (iSert and Tecnis iTec) and a manual system (Monarch III D) in terms of IOL placement in porcine eyes.
- Results showed that the Ultrasert system resulted in the least corneal incision enlargement and had fewer complications compared to the other systems, specifically noting issues with nozzle tip splitting and IOL adherence in the other systems.
- The conclusion highlighted that the Ultrasert system’s design facilitated smoother IOL delivery and required the smallest increase in incision size, making it a more effective option than the ones tested.
Objective: To compare effects of medetomidine and xylazine hydrochloride on results of cystometry and micturition reflexes in healthy dogs and results of urethral pressure profilometry (UPP) in sedated and conscious dogs.
Animals: 20 dogs.
Procedures: Urodynamic testing was performed 6 times in each dog (3 times after administration of xylazine [1 mg/kg of body weight, IV] and 3 times after administration of medetomidine (30 microg/kg, IM).
The role of focal brain damage as a trigger for autoimmune inflammation in multiple sclerosis (MS) is unclear. In this study we examine mechanisms by which experimental autoimmune encephalomyelitis (EAE) is enhanced by focal brain damage. EAE was produced in Lewis rats by footpad inoculation; focal brain damage, in the form of a cortical cryolesion (cryolesion-EAE), was induced 8 days post-inoculation (d.
View Article and Find Full Text PDFObjective: To characterize urodynamic function and anatomy before and after colposuspension in anesthetized female Beagles.
Animals: 12 adult female Beagles. PROCEDURE; During general anesthesia (thiopental sodium induction and halothane maintenance), urethral pressure profiles, leak point pressure measurements with a 50-ml bladder volume, positive contrast cystograms, and retrograde vaginourethrocystograms were performed.