Deficits in egocentric-updating and spatial context memory in a case of developmental amnesia.

Patients with developmental amnesia usually suffer from both episodic and spatial memory deficits. DM, a developmental amnesic, was impaired in her ability to process self-motion (i.e.

Apathy in aging: are lack of interest and lack of initiative dissociable?

Apathy is common in aging and generally defined on the basis of three dimensions: lack of initiative, lack of interest and emotional blunting. Curiously, no study until now has examined the associations and dissociations between these dimensions in elderly people (with or without dementia). These questions were addressed in two studies.

The role of feature sharedness in the organization of semantic knowledge: insights from semantic dementia.

Objective: The present study directly evaluated the impact of feature sharedness on the differences between superordinate and basic-level concepts observed in semantic dementia (SD) patients.

Method: For this purpose, we studied a group of 6 SD patients and a group of 12 matched controls using a sentence verification task in which we orthogonally manipulated feature sharedness (more vs. less shared) and concept level (basic level vs.

Spatial deficits in an amnesic patient with hippocampal damage: questioning the multiple trace theory.

Mediotemporal lobe structures are involved in both spatial processing and long-term memory. Patient M.R.

Apathy and executive dysfunction in Alzheimer disease.

Apathy, defined as a reduction in voluntary goal-directed behaviors, is one of the most common behavioral symptoms encountered in Alzheimer disease (AD). However, the processes underlying the different components of apathy are still unclear. The aim of this study was to explore a particularly important aspect of executive function in daily life: multitasking [assessed with the Modified Six Elements Task (MSET)], and its relationship with apathy in AD.