Publications by authors named "A Chapwanya"

Article Synopsis
  • Understanding reproductive success in domestic animals requires knowledge of sperm biology, fertilization, and conception processes.
  • Key focus areas include sperm maturation, capacitation, the acrosome reaction, and gamete recognition for successful fertilization.
  • Future research will advance reproductive techniques by examining molecular biology, immune interactions, environmental impacts, and multi-omics approaches to enhance fertility outcomes.
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This review paper delves into the intricate relationship between the genital microbiome and fertility outcomes in livestock, with a specific focus on cattle. Drawing upon insights derived from culture-independent metagenomics studies, the paper meticulously examines the composition and dynamics of the genital microbiome. Through advanced techniques such as high-throughput sequencing, the review illuminates the temporal shifts in microbial communities and their profound implications for reproductive health.

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Proteomics, the large-scale study of proteins in biological systems has emerged as a pivotal tool in the field of animal and veterinary sciences, mainly for investigating local and rustic breeds. Proteomics provides valuable insights into biological processes underlying animal growth, reproduction, health, and disease. In this review, we highlight the key proteomics technologies, methodologies, and their applications in domestic animals, particularly in the tropical context.

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Article Synopsis
  • - The study focused on assessing the bacterial load and molecular details of Coxiella burnetii in pregnant and postpartum ewes from Saint Kitts, using previously collected positive samples from Barbados Blackbelly ewes.
  • - Techniques like real-time qPCR were employed to analyze various samples (vaginal mucus, feces, and milk) for the presence of C. burnetii DNA, revealing equal amounts of bacterial DNA across these sample types.
  • - Molecular characterization showed a high diversity of C. burnetii haplotypes, indicating they are widespread, with similarities found in other ruminants and even ticks and humans.
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Uterine disease in cattle impairs reproductive performance and profitability and increases antibiotic use and antimicrobial resistance. Thus, probiotics offer a promising alternative therapy. This review presents conceptual findings on the efficacy of probiotics in managing uterine diseases and fertility in cows.

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