Publications by authors named "A Chaparro"

Purpose: To assess the rate of heterotopic ossification (HO) following acetabular surgery with a standardized protocol via the Kocher-Langenbeck. Secondarily, to evaluate patient characteristics, injury variables, and perioperative data among patients with HO and no HO.

Methods: This was a retrospective case series from an academic Level I trauma center.

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  • The study aimed to assess the knowledge and experiences of family members and medical staff regarding oral health care for older adults with cognitive impairment and Alzheimer's disease.
  • Through interviews with 30 participants, the researchers gathered insights that revealed a general lack of knowledge and understanding about oral hygiene practices and their importance among both family members and formal caregivers.
  • Findings indicated a need for better education and resources to help caregivers provide adequate oral health care, highlighting its critical role in enhancing the quality of life for older adults.
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  • Cushing's disease (CD) co-occurring with chronic kidney disease (CKD) is rare and makes diagnosis challenging due to CKD-induced hypercortisolism; this report presents three female cases to improve understanding of diagnosis in such contexts.
  • Each patient, aged between 12 and 16, had various CKD-related conditions and presented symptoms typical of CD, which were confirmed through clinical and biochemical evaluations; surgical interventions led to remission, but some patients developed pituitary deficiencies.
  • These cases highlight the need for careful clinical assessment in diagnosing CD among CKD patients, as clear diagnostic criteria are currently lacking.
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Aim: To characterize the gingival crevicular fluid (GCF) and plasma extracellular vesicles (EVs) and explore their proteomic cargo in healthy pregnant women compared to those with gestational diabetes mellitus (GDM) and periodontitis.

Methods: One-hundred and four pregnant women were recruited at 24-30 gestation weeks. GDM was diagnosed by an oral glucose tolerance test.

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Aim: Epigenetic regulation of the key inflammatory genes plays a crucial role in controlling monocyte/macrophage-mediated local and systemic responses to bacterial challenges. However, it has not been addressed in apical periodontitis (AP). We aimed to explore the methylation pattern of the TNF-α gene promoter and its association with the inflammatory phenotype of peripheral blood monocytes from individuals with AP and controls.

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