[Pharmalogic effects of benzonitrile on the central nervous system].

The present experiments intended to explore the psychopharmacological properties of benzonitrile on mice. Benzonitrile decreased motility, muscular force and inquisitiveness. The hypnotic effects of chloral and pentobarbital were increased by benzonitrile.

[Pharmacologic effects of glycerolformal on the central nervous system].

Glycerolformal is not devoid of action on mice psychomotor behaviour. Administered through the digestive tract with infralethal doses, it can exercice depressing effects on muscular strength and sensitivity to pain without affecting inquisitiveness. It opposes the stimulating effects specific to pentetrazol, amphetamine and apomorphine and is a protection against electric convulsions but tends to increase the toxicity of tryptamine.