Highly multiplexed imaging reveals prognostic immune and stromal spatial biomarkers in breast cancer.

Spatial profiling of tissues promises to elucidate tumor-microenvironment interactions and generate prognostic and predictive biomarkers. We analyzed single-cell, spatial data from three multiplex imaging technologies: cyclic immunofluorescence (CycIF) data we generated from 102 breast cancer patients with clinical follow-up, and publicly available imaging mass cytometry and multiplex ion-beam imaging datasets. Similar single-cell phenotyping results across imaging platforms enabled combined analysis of epithelial phenotypes to delineate prognostic subtypes among estrogen-receptor positive (ER+) patients.

Secure data communication in WSHN using EXP-MD5 and DHSK-ECC.

Background: In the Healthcare (HC) sector, the usage of Wireless Sensor Healthcare Networks (WSHN) is attaining specific importance. The sensor device is implanted into the patient's body, and the sensed health information of patients is transformed via data aggregating devices like mobile devices, cameras, and so on, to the doctors. Thus, the early signs of diseases are identified, and remote monitoring of the patient's health is carried out by the physician on time.

Advancing healthcare: the role and impact of AI and foundation models.

Background: The integration of artificial intelligence (AI) into the healthcare domain is a monumental shift with profound implications for diagnostics, medical interventions, and the overall structure of healthcare systems.

Purpose: This study explores the transformative journey of foundation AI models in healthcare, shedding light on the challenges, ethical considerations, and vast potential they hold for improving patient outcome and system efficiency. Notably, in this investigation we observe a relatively slow adoption of AI within the public sector of healthcare.

The push-pull intercrop does not repel, but intercepts and kills pests.

Over two decades ago, an intercropping strategy was developed that received critical acclaim for synergizing food security with ecosystem resilience in smallholder farming. The push-pull strategy reportedly suppresses lepidopteran pests in maize through a combination of a repellent intercrop (push), commonly spp., and an attractive, border crop (pull).