Publications by authors named "A Chadwick"

Article Synopsis
  • The study investigates CP symmetry violation in the decay of D^{+} particles into K^{-}K^{+}π^{+} using data from proton-proton collisions at a high energy of 13 TeV.
  • A unique model-independent method was employed to analyze the phase-space distributions of D^{+} and D^{-} particles, correcting for any instrumental biases using D_{s}^{+} decays.
  • The findings indicate no significant evidence of CP violation, with a p value of 8.1%, and measure specific CP asymmetry observables, marking this study as the most sensitive search of its kind in multibody decays.
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This good practice paper (GPP) is intended to support clinicians in assessing patient fitness for bleomycin and in management of bleomycin pulmonary toxicity (BPT) where it occurs. Bleomycin, originally developed as an antibiotic in the 1960s, has been a cornerstone of therapy for classical Hodgkin lymphoma (CHL) since results of its use in combination with doxorubicin, vincristine and dacarbazine (ABVD) were first published by Bonadonna et al in 1975 1. The same author recognised high rates of respiratory morbidity in these patients 2, and bleomycin-;related pulmonary toxicity (BPT) is now a well-;recognised and feared complication with its use.

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Article Synopsis
  • - Menopause occurs between ages 45 and 55, marking the end of a woman's reproductive years, and often involves overlooked pain such as musculoskeletal discomfort, headaches, and vulvovaginal pain.
  • - The causes of menopausal pain are complex, tied to hormonal changes, psychosocial factors, and genetics, which can worsen perception of pain due to issues like mood disorders and lack of sleep.
  • - The article calls for more research to better understand menopausal pain and emphasizes the importance of effective management strategies to improve the wellbeing and quality of life for women during this transition.
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Tolvaptan is a vasopressin V2 receptor antagonist which has proven to be an effective and mostly well-tolerated agent for the treatment of autosomal-dominant polycystic kidney disease. However, its administration is associated with rare but serious idiosyncratic liver injury, which has warranted a black box warning on the drug labels and frequent monitoring of liver blood tests in the clinic. This review outlines mechanistic investigations that have been conducted to date and constructs a working narrative as an explanation for the idiosyncratic drug-induced liver injury (IDILI) events that have occurred thus far.

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Article Synopsis
  • A study was conducted on B^{+} decays to explore resonant structures using data from the LHCb experiment at various energy levels, totaling an integrated luminosity of 9 fb^{-1}.
  • The researchers performed a simultaneous amplitude fit on two decay channels, determining the C parities of resonances in the D^{*±}D^{∓} mass spectra.
  • Four new charmonium or charmoniumlike states were discovered, including η_{c}(3945) and h_{c}(4000), and the presence of T_{c[over ¯]s[over ¯]0}^{*}(2870)^{0} and T_{c[over ¯]s
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