Publications by authors named "A Ch Darabi"
Article Synopsis
- Obesity is associated with nephrolithiasis (kidney stones), especially in older adults, prompting this study to explore how various obesity-related indices relate to this condition.
- The study involved 2,419 older adults, analyzing data from the Bushehr Elderly Health program, and found that specific fat distribution ratios were linked to a history of kidney stones.
- Key findings revealed significant associations between nephrolithiasis and fat ratios, with differences noted between genders—highlighting the importance of monitoring these indices for better health outcomes in the elderly.
Article Synopsis
- The study investigates the connection between osteosarcopenia, a condition combining bone and muscle loss, and COVID-19 mortality in hospitalized patients in Bushehr, Iran, highlighting the increased risks associated with this syndrome in older adults.
- Out of 4,173 participants, 297 were hospitalized for COVID-19, with 80 fatalities; those with osteosarcopenia showed significantly higher mortality rates and increased risk for severe outcomes like ICU admission.
- The findings suggest that assessing musculoskeletal issues like osteosarcopenia in older COVID-19 patients could serve as an early warning for potential severe illness and help guide patient management.
Glioblastoma presents a formidable clinical challenge because of its complex microenvironment. Here, we characterized tumor-associated foam cells (TAFs), a type of lipid droplet-loaded macrophage, in human glioblastoma. Through extensive analyses of patient tumors, together with in vitro and in vivo investigations, we found that TAFs exhibit distinct protumorigenic characteristics related to hypoxia, mesenchymal transition, angiogenesis, and impaired phagocytosis, and their presence correlates with worse outcomes for patients with glioma.
View Article and Find Full Text PDFIn this study, we quantitatively investigate the impact of 1.4 wt.% chromium and 1.
View Article and Find Full Text PDFBackground: Using next-generation sequencing technologies, scientists can sequence complex microbial communities directly from the environment. Significant insights into the structure, diversity, and ecology of microbial communities have resulted from the study of metagenomics. The assembly of reads into longer contigs, which are then binned into groups of contigs that correspond to different species in the metagenomic sample, is a crucial step in the analysis of metagenomics.
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