Publications by authors named "A Cetina Herrando"
Article Synopsis
- Colorectal cancer (CRC) is a common global concern, prompting research into defining methods for characterizing its tissues; this study examines the autofluorescence of colorectal tissues from 73 patients post-surgery.
- The research utilized an advanced optical imaging system to analyze the autofluorescence characteristics of collagens, NAD(P)H, and flavins, revealing key differences between normal, adenomatous, and cancerous tissues linked to the underlying clinicopathological features.
- Findings show that changes in autofluorescence signatures, influenced by tumor characteristics and treatment effects, suggest potential for these measurements to improve CRC clinical practices from diagnosis to management and future research directions.
Advancements in optical imaging techniques have revolutionized the field of biomedical research, allowing for the comprehensive characterization of tissues and their underlying biological processes. Yet, there is still a lack of tools to provide quantitative and objective characterization of tissues that can aid clinical assessment in vivo to enhance diagnostic and therapeutic interventions. Here, we present a clinically viable fiber-based imaging system combining time-resolved spectrofluorimetry and reflectance spectroscopy to achieve fast multiparametric macroscopic characterization of tissues.
View Article and Find Full Text PDFColorectal cancer is currently the third most frequently diagnosed type of cancer and the second cause of cancer death in the western world. Inflammatory bowel disease patients are 2-6 times more likely to develop CRC than the general population. Patients with CRC arising through Inflammatory Bowel Disease have an indication for surgery.
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