Emerging Drug Therapies for Inherited Retinal Dystrophies.

Worldwide, 1 in 2000 people suffer from inherited retinal dystrophies (IRD). Individuals with IRD typically present with progressive vision loss that ultimately results in blindness. Unfortunately, effective treatment options are not widely available due to the genetic and clinical heterogeneity of these diseases.

Metal free, full arch, fixed prosthesis for edentulous mandible rehabilitation on four implants.

Purpose: The goal of this work is to describe an implant-prosthetic protocol for rehabilitation of edentulous mandible, by using a fixed prosthesis made of fiber-reinforced composite material (FRC). The protocol contemplates a minimal invasive surgery and ensures predictable and safe results, with good aesthetic and performance combined to cost savings.

Methods: FRC material is used to build the substructure of a prosthetic framework supported by four short implants (5mm long and 4mm wide).