Chitosan-Mediated Environment-Friendly Synthesis of Gold Nanoparticles with Enhanced Photonic Reactivity.

We developed a very simple, efficient and environment-friendly synthesis method for the manufacturing of high-performance chitosan-capped gold nanoparticles that could be used for biosensing applications. Gold nanoparticles were prepared through the spontaneous reduction of chloroauric acid by chitosan, which was used as both a reducing and a stabilizing agent. The samples were heated to a temperature of 60 °C under ultrasonic conditions.

Ketoprofen-liposomes formulation for clinical therapy.

Lipid (L-α-phosphatidylcholine) was used in liposome-ketoprofen formulation to obtain vesicles systems characterized by a net positive charge along the liposomal surface. A careful analysis of vesicles formation and systems stability was made. Dynamic stability and specificity of liposomes disruption and prolonged release of ketoprofen was provided by steric effect accomplished on the vesicle surface by chitosan molecules, which were introduced into the system additionally.

Use of fresh decellularized allografts for pulmonary valve replacement may reduce the reoperation rate in children and young adults: early report.

Background: Degeneration of xenografts or homografts is a major cause for reoperation in young patients after pulmonary valve replacement. We present the early results of fresh decellularized pulmonary homografts (DPH) implantation compared with glutaraldehyde-fixed bovine jugular vein (BJV) and cryopreserved homografts (CH).

Methods And Results: Thirty-eight patients with DPH in pulmonary position were consecutively evaluated during the follow-up (up to 5 years) including medical examination, echocardiography, and MRI.

Dynamic hybrid materials for constitutional self-instructed membranes.

Constitutional self-instructed membranes were developed and used for mimicking the adaptive structural functionality of natural ion-channel systems. These membranes are based on dynamic hybrid materials in which the functional self-organized macrocycles are reversibly connected with the inorganic silica through hydrophobic noncovalent interactions. Supramolecular columnar ion-channel architectures can be generated by reversible confinement within scaffolding hydrophobic silica mesopores.