Publications by authors named "A Cavadino"
To compare lighting levels in care facilities with local recommendations and determine their cross-sectional association with fall rate, we recruited residents ( = 126) from 12 long-term care facilities (mean ± SD age 85.1 ± 7.9 years; 64.
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- The study investigates acute respiratory distress syndrome (ARDS) in ICU patients from Australia and New Zealand, focusing on patient characteristics and management practices during a multi-center analysis.
- Among the 200 participants, the average age was 55.5 years; notable findings included a low adherence to lung protective ventilation (only 10.5% on day one) and significant use of adjunctive therapies like systemic steroids.
- The in-hospital mortality rate by day 28 was 30.5%, highlighting the need for improved implementation of established treatment protocols in ARDS care.
LSDDEP2: study protocol for a randomised, double-dummy, triple-blind, active placebo-controlled, parallel groups trial of LSD microdosing in patients with major depressive disorder.
Trials
August 2024
Background: Major depressive disorder (MDD) poses a significant global health burden with available treatments limited by inconsistent efficacy and notable side effects. Classic psychedelics, including lysergic acid diethylamide (LSD), have garnered attention for their potential in treating psychiatric disorders. Microdosing, the repeated consumption of sub-hallucinogenic doses of psychedelics, has emerged as a self-treatment approach for depression within lay communities.
View Article and Find Full Text PDFOutcomes from low-risk ductal carcinoma in situ: a systematic review and meta-analysis.
Breast Cancer Res Treat
November 2024
Purpose: The current standard of treatment for ductal carcinoma in situ (DCIS) is surgery with or without adjuvant radiotherapy. With a growing debate about overdiagnosis and overtreatment of low-risk DCIS, active surveillance is being explored in several ongoing trials. We conducted a systematic review and meta-analysis to evaluate the recurrence of low-risk DCIS under various treatment approaches.
View Article and Find Full Text PDFBackground: This study aimed to compare the demographic differences between Māori and NZ Europeans with neck of femur fracture (NOF), identify any differences in management, surgical and post-op care and outcomes.
Methods: All cases in New Zealand between 2018 and 2020 were collected from the Australia & New Zealand Hip Fracture Registry (ANZHFR). Basic demographics, management factors, and surgical factors were collected.