Publications by authors named "A Castiglioni"

Objectives: Mitral regurgitation due to anterior mitral leaflet lesions is associated with an increased risk of mitral regurgitation recurrence after mitral valve repair compared with posterior leaflet-related lesions. Both edge-to-edge (E-to-E) and neochordal repair, associated with ring annuloplasty, have been used in our institution to address isolated anterior mitral leaflet lesions. The aim of this study was to compare the clinical and echocardiographic long-term results of those two approaches for isolated anterior mitral leaflet lesions by means of a propensity match analysis.

View Article and Find Full Text PDF
Article Synopsis
  • The left atrium (LA) plays an active role in heart function, and its impaired compliance in severe mitral regurgitation (MR) can lead to increased pressures and symptoms like dyspnea.
  • This study analyzes LA function in patients with severe degenerative MR to see how it correlates with symptom onset, classifying patients into symptomatic and asymptomatic groups.
  • Results indicate that LA dysfunction is significantly linked to symptoms, with a specific marker (LASr) being a strong predictor, suggesting that recognizing LA dysfunction can help manage asymptomatic patients effectively.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate how well right ventricular free wall longitudinal strain can predict peri-operative mortality in patients with severe tricuspid regurgitation undergoing tricuspid valve surgery, compared to traditional risk scores.
  • Researchers analyzed data from 110 patients, ultimately focusing on 79 who met criteria, finding that 9% died within 30 days post-surgery.
  • Results showed that right ventricular free wall longitudinal strain was the strongest predictor of mortality, outperforming classic risk scores when combined, indicating its potential importance in patient assessment before surgery.*
View Article and Find Full Text PDF

The bicuspid aortic valve (BAV) is the most common congenital cardiac abnormality. Though most often isolated, BAV may be associated with other cardiovascular malformations. BAV-related aortopathy is the most common, sharing genetic alterations and phenotypic heterogeneity characteristics.

View Article and Find Full Text PDF

Aims: The prevalence, the aetiologies, and the clinical features of tricuspid regurgitation (TR) in the context of concomitant degenerative mitral valve (MV) disease are poorly defined. This paper aims to assess the prevalence, determinants, and clinical consequences of TR in severe degenerative mitral regurgitation (DMR).

Methods And Results: Clinical and echocardiographic characteristics were collected among patients with severe DMR.

View Article and Find Full Text PDF