Radiotherapy for genital extramammary Paget's disease in situ.

Background: Radiotherapy as a first-choice treatment for extramammary Paget's (EMP) disease in situ has been seldom used.

Objective: To review the most relevant aspects of radiotherapy as first-choice treatment in selected cases of anogenital EMP disease in situ.

Methods: Two men with an age range of 71-79 years (mean age 75 +/- 5.

[Hepato-erythrocytic porphyria. A new type of porphyria].

A case of porphyria with symptomatology beginning in early infancy with peculiar biochemical features is described. There were crops of blisters, an extraordinary hypertrichosis and scarring of the exposed skin. The porphyrin examination showed an abnormal excretion pattern of urinary porphyrins with large amounts of 5-COOH carboxyle porphyrins and the protoporphyrin level of the red cells was raised.