Publications by authors named "A Cassels"
Background: Proton pump inhibitors (PPIs) are one of the most used classes of drugs. For most indications, PPIs are only recommended up to 8 weeks duration. However, PPI use continues to expand.
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- Polypharmacy negatively impacts older adults' health, with issues like medication interactions and adherence playing significant roles. This study sought to explore ways to reduce polypharmacy through a clinical pathway in primary care.
- Patients aged 70 and older were randomized into intervention (TAPER program) or control groups, with TAPER focusing on personalized medication management and monitoring through a web-based system called TaperMD.
- The study successfully met all feasibility criteria for implementing TAPER, showing promise for a larger randomized controlled trial to further investigate its effects on health outcomes.
Background: Polypharmacy in older adults can be associated with negative outcomes including falls, impaired cognition, reduced quality of life, and general and functional decline. It is not clear to what extent these are reversible if the number of medications is reduced. Primary care does not have a systematic approach for reducing inappropriate polypharmacy, and there are few, if any, approaches that account for the patient's priorities and preferences.
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