Publications by authors named "A Casetta"
Background: Accidental exposure to blood (AEB) poses a risk of bloodborne infections for healthcare workers (HCWs) during hospital activities. In this study, we identified individual behavioral and organizational predictors of AEB among HCWs.
Methods: The study was a prospective, 1-year follow-up cohort study conducted in university hospitals in Paris, France.
Article Synopsis
- The incidence of Clostridium difficile infection (CDI) has risen over the past 20 years, with asymptomatic carriers potentially serving as important reservoirs in healthcare settings.* -
- A study conducted from September 2019 to January 2020 in 11 hospitals in Paris included 2,389 patients over 3 years old, revealing a 3.2% asymptomatic carriage rate of toxigenic strains of CDI.* -
- Key factors associated with increased asymptomatic carriage were co-carriage of multidrug-resistant organisms and previous CDI history, while consuming raw milk products appeared to lower the risk.*
Objectives: Since 2003, incidences of carbapenemase-producing Gram-negative bacilli (CP-GNB) and vancomycin-resistant Enterococcus faecium (VRE) have steadily increased in France. We therefore conducted a point prevalence study to estimate carriage rates of CP-GNB, VRE and ESBL-producing Enterobacterales (ESBL-PE) and associated risk factors.
Methods: Between September 2019 and January 2020, all inpatients hospitalized on a given day in 11 teaching hospitals in the Paris urban area were eligible.
Objective: Healthcare workers (HCWs) are at high risk of experiencing stress and fatigue due to the demands of their work within hospitals. Improving their physical and mental health and, in turn, the quality and safety of care requires considering factors at both individual and organisational/ward levels. Using a multicentre prospective cohort, this study aims to identify the individual and organisational predictors of stress and fatigue of HCWs in several wards from university hospitals.
View Article and Find Full Text PDFAntimicrobial stewardship in high-risk febrile neutropenia patients.
Antimicrob Resist Infect Control
March 2022
Article Synopsis
- The study evaluates the impact of an antimicrobial stewardship (AMS) program based on ECIL4 guidelines for antibiotics de-escalation in febrile neutropenia (FN) patients, comparing data from before and after the implementation.
- Conducted at Cochin University Hospital, the observational study analyzed 273 hospital stays pre-intervention and 217 post-intervention, focusing on antibiotic use and clinical outcomes.
- Results showed substantial reductions in the use of glycopeptides and carbapenems (85% and 72% respectively), along with a significant decrease in the risk of ICU transfers or death, indicating the effectiveness of the AMS program.