Publications by authors named "A Carozza"
Article Synopsis
- The study examined the short- and long-term mortality rates of infective endocarditis (IE) among people who inject drugs (PWID) by analyzing data from hospitalized patients between 2000 and 2021.
- Out of 485 IE patients, 55 (11%) were PWID, who were matched with 55 non-intravenous drug users (N-IDU) based on age and sex; PWID had higher rates of HCV co-infection and advanced liver disease.
- Findings indicated that PWID faced a nearly threefold increased risk of long-term mortality after being hospitalized for IE compared to the N-IDU group, highlighting the need for further investigation into the factors contributing to their elevated mortality risk
Streptococci still represent common etiologic agents of infective endocarditis (IE). Although renal failure is frequently reported as an aminoglycoside-associated adverse event, last international guidelines recommend a beta-lactam/gentamicin combination therapy. We retrospectively evaluated the use of daptomycin-based aminoglycoside-sparing combination therapy for the treatment of streptococcal IE in seven referral hospitals in Italy.
View Article and Find Full Text PDFBackground: Infective endocarditis (IE) is characterized by high rates of in-hospital death, and Staphylococcus aureus infection predicts a worse prognosis. We aimed to assess if admission inflammatory biomarkers (white blood cell - WBC - count, C-reactive protein - CRP, and procalcitonin) are informative on microbiological etiology and short-term outcomes.
Methods: Data from 236 patients admitted for IE from January 2013 to June 2018 were retrieved from a multicenter registry.