Publications by authors named "A Cardone"
Article Synopsis
- The study examined how full vaccination and the timing of vaccinations affected SARS-CoV-2 infection rates among healthcare workers (HCWs) in Italy's Marche Region.
- 81.2% of HCWs in the cohort were fully vaccinated, with factors such as age, role, and prior health status influencing vaccination rates.
- Vaccination reduced infection risk by 77%, particularly for those vaccinated earlier, highlighting the need for effective vaccination strategies for all HCWs.
Background: Patients receiving chemotherapy require ongoing symptom monitoring and management to optimize their outcomes. In recent years, digital remote monitoring interventions have emerged to provide enhanced cancer care delivery experiences to patients and clinicians. However, patient and clinician experiential evaluations of these technologies are rare.
View Article and Find Full Text PDFImmigrants from Asian countries are the fastest-growing undocumented population in the United States (U.S.), yet not much is known about their health.
View Article and Find Full Text PDFNavigating the path towards successful implementation of the EU HTA Regulation: key takeaways from the 2023 Spring Convention of the European Access Academy.
Health Res Policy Syst
July 2024
Background: The European Regulation on Health Technology Assessment (EU HTA R), effective since January 2022, aims to harmonize and improve the efficiency of common HTA across Member States (MS), with a phased implementation from January 2025. At "midterms" of the preparation phase for the implementation of the Regulation our aim was to identify and prioritize tangible action points to move forward.
Methods: During the 2023 Spring Convention of the European Access Academy (EAA), participants from different nationalities and stakeholder backgrounds discussed readiness and remaining challenges for the Regulation's implementation and identified and prioritized action points.
Article Synopsis
- Munc18-1 is a key protein that facilitates vesicle fusion and neuronal exocytosis by interacting with Syntaxin1, crucial for neurotransmitter release.
- Recent research highlights the peptide p5 as a potential drug for targeting the CDK5-p25 complex in Alzheimer's disease, with Munc18-1 playing a role in its selective inhibition without disrupting normal CDK5 function.
- This paper explores how p5 interacts with Munc18-1, affecting its binding to SNARE proteins and potentially leading to off-target effects, while discussing implications for therapeutic efficacy and safety in treating neurodegenerative diseases.