Publications by authors named "A Cappuccio"

Background: Despite the effectiveness of inhalation therapy, uncontrolled or severe asthma remains prevalent challenges in respiratory care Narrative Medicine (NM) offers a linguistic approach to comprehending illness experiences, thereby providing a framework for advancing healthcare.

Aim: The primary aim of this study was to gather narratives from individuals grappling with severe or uncontrolled asthma and their Healthcare Professionals (HCPs), in order to explore the intricate interplay among quality of care, quality of life, psychological and social determinants, and adherence patterns.

Methods: A cross-sectional NM study was conducted in Italy from February to December 2023, encompassing 135 patients with uncontrolled or severe asthma (54.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to investigate how smoking exposure is linked to organ damage in patients with systemic lupus erythematosus (SLE) using a specific damage score (SLICC-SDI) in an Argentinian cohort.
  • Out of 623 SLE patients analyzed, 84% were non-smokers, while 16% were current smokers, with 17% showing severe organ damage (SLICC-SDI ≥3).
  • The findings indicated that current smoking, older age, longer disease duration, and the use of cyclophosphamide are significantly associated with severe organ damage in SLE patients.
View Article and Find Full Text PDF
Article Synopsis
  • SPEEDI is an automated framework designed for single-cell multi-omics analysis, aiming to simplify data integration and cell-type labeling.
  • It transforms diverse data from different samples into a cohesive dataset without requiring any user intervention, making the process more reproducible.
  • The tool also facilitates downstream analyses, such as assessing differential signals and gene functions, and is compatible with existing integration and cell-typing tools.
View Article and Find Full Text PDF

Introduction: Despite an improved understanding of its pathogenesis, dry eye disease (DED) remains relatively underestimated and its treatment challenging. A better alignment between the clinical evaluation and the patient self-assessment also requires capturing the whole patient experience of DED. This project aimed to unveil this experience through narrative medicine (NM).

View Article and Find Full Text PDF