Publications by authors named "A Cappella"

Background/objectives: Facial asymmetry is gaining an increasing diagnostic interest in many clinical contexts. Several three-dimensional surface-based methods have been proposed for its assessment; however, they might provide non-equivalent data. Since there is a lack of comparative studies in these terms, this study aims to compare three methods for assessing the asymmetry of the face and facial thirds, thus addressing whether the potential differences can be considered clinically acceptable or not.

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  • The study explores the benefits of 3D analysis of maxillofacial structures in patients with dysmorphic conditions, emphasizing the increased accuracy and precision over 2D methods, particularly in cases of cleft lip/palate (CL/P) or other syndromes.
  • A scoping review analyzed 17 out of over 4,500 articles to evaluate current 3D surface imaging methods for volumetric analysis and identify existing protocols and reference data, following strict inclusion criteria.
  • The findings revealed significant variability among the studies, indicating a lack of standardized methods and protocols, which underscores the need for collective efforts to establish uniform practices and enhance the quality of scientific evidence in the field.
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  • The study focuses on using 3D techniques to match the atlas and axis bones at the atlantoaxial joint, which is key in forensic contexts for assembling disarticulated bodies.
  • Researchers found that they could distinguish between matched and unmatched bones using point-to-point distance measurements (RMS), achieving a sensitivity of 100% for identifying correct matches.
  • The findings suggest that while this 3D-3D superimposition method isn't definitive for re-association, it serves as a useful screening tool, warranting further exploration in the study of other joints.
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  • Forensic anthropologists are exploring the use of "secondary identifiers," like pigmented skin lesions (PSLs), to help identify human remains when typical methods are limited.
  • A study analyzed 1,039 Italian subjects to gather data on the prevalence and distribution of facial PSLs, focusing on size and position across different facial areas.
  • The findings suggested that these PSLs can be highly effective in personal identification (PI) when combined with other data, but further research is needed to validate their reliability and significance in forensic contexts.
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A hypercaloric fatty diet predisposes an individual to metabolic syndrome and cardiovascular complications. Sirtuin1 (SIRT1) belongs to the class III histone deacetylase family and sustains anabolism, mitochondrial biogenesis, and fat distribution. Epididymal white adipose tissue (eWAT) is involved in inflammation, whilst interscapular brown adipose tissue (iBAT) drives metabolism in obese rodents.

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