[Correlations between Doppler velocimetry, arteriography and intraoperative findings in the study of carotid vascular diseases].

The present paper reports the results obtained in 54 patients who underwent a non invasive cerebral vascular examination by doppler technique, followed by a cerebral angiography: a total of 86 carotid arteries were compared. An overall accuracy between arteriographic and ultrasonographic results was found in 69 arteries whereas in 15 arteries there was a discordance; and in only 3 cases ultrasonographic findings resulted false negative. The Authors have also considered the emodinamic and anatomo pathological results obtained in 23 carotid arteries operated on, in order to evaluate ophthalmic test accuracy and noninvasive evaluation of Willis's circle.

Induction of gene mutations and gene conversions by vinyl chloride metabolites in yeast.

Chloroethylene oxide and 2-chloroacetaldehyde, two metabolites of vinyl chloride, and 2-chloroethanol, a putative metabolic intermediate, were assayed for their genetic activity in the yeasts Schizosaccharomyces pombe and Saccharomyces cerevisiae. Chloroethylene oxide was found to be the most effective in inducing forward mutations in Sch. pombe and gene conversions in S.