Publications by authors named "A Caminati"
Article Synopsis
- Lymphangioleiomyomatosis is a rare lung disease primarily affecting women, and the study investigates the safety and effectiveness of the multikinase inhibitor nintedanib after sirolimus has been deemed insufficient or unsuitable.
- Conducted in Milan, the phase 2 study included 30 women who took nintedanib for 12 months, with the main measurement being the change in lung function (FEV) over that period.
- Results showed that participants experienced stable lung function after one year on nintedanib, but a slight decline occurred in lung function during the following year without treatment, with nausea being the most common side effect.
Echocardiographic evaluation of left ventricular mechanics in sarcoidosis patients without overt heart disease: a systematic review and meta-analysis.
Sarcoidosis Vasc Diffuse Lung Dis
September 2024
Background And Aim: During the last decade, a small number of studies have used speckle tracking echocardiography (STE) to investigate sarcoidosis effect on left ventricular (LV) mechanics in patients without overt heart disease. The present systematic review and meta-analysis has been primarily designed to summarize the main findings of these studies and to examine the overall influence of sarcoidosis on LV-global longitudinal strain (GLS) and left ventricular ejection fraction (LVEF).
Methods: All echocardiographic studies assessing conventional echoDoppler parameters and myocardial strain indices in patients with extracardiac sarcoidosis (ECS) vs.
Vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is a recently characterized disease associated with somatic mutations in the UBA1 gene, which cause dysregulation of ubiquitin-mediated processes. This case describes a 71-year-old male patient with VEXAS syndrome who presented with refractory lung inflammation with a pattern similar to computed tomography hypersensitivity pneumonitis, a novel finding in VEXAS syndrome. The presented clinical case highlights the protean involvement of the lung in VEXAS syndrome and emphasizes the importance of considering interstitial lung disease in the differential diagnosis.
View Article and Find Full Text PDFTAPSE/SPAP ratio stratifies mortality risk in mild-to-moderate idiopathic pulmonary fibrosis.
Int J Tuberc Lung Dis
April 2024
BACKGROUND: Due to paucity of literature data, we aimed at evaluating the prognostic role of the ratio of tricuspid annular plane systolic excursion (TAPSE) to systolic pulmonary artery pressure (SPAP) in idiopathic pulmonary fibrosis (IPF) patients without severe pulmonary hypertension and at assessing its correlation with effective arterial elastance index (EaI). METHODS: Multi-instrumental data obtained in 60 IPF patients (73.2 ± 6.
View Article and Find Full Text PDF