Publications by authors named "A Camara"
Background: α-Synuclein (SNCA) gene hypomethylation was reported in idiopathic Parkinson's disease (iPD). Based on a high clinical resemblance between iPD and leucine-rich repeat kinase 2 (LRRK2)-driven Parkinson's disease (L2PD), we investigated the epigenetic status of SNCA in an extensive LRRK2 clinical cohort from Spain.
Methods: We assessed the methylation levels of 23 CpG sites in the SNCA promoter region using peripheral blood DNA from L2PD patients (n = 151), LRRK2 nonmanifesting carriers (n = 55), iPD patients (n = 115), and healthy control subjects (n = 154) (total: N = 475).
Children with sickle cell anemia (SCA) experience recurrent vaso-occlusive crises and complications, significantly impacting their health-related quality of life (HRQoL). This study determined HRQoL in 130 children aged 5 -15 years with SCA in The Gambia, compared to 130 age- and sex-matched hemoglobin AA (HbAA) children. HRQoL was measured using the Pediatric Quality of Life Inventory (PedsQL), with scores below 69.
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- Yeasts play a crucial role in artisanal cheese production by inhibiting harmful species and contributing to flavor development.
- The study extensively mapped the yeast diversity in 582 central Brazilian artisanal cheese samples, identifying over 300 clusters, including key species like Torulaspora delbrueckii and Yarrowia lipolytica.
- Findings highlight the diverse yeast populations in Brazilian cheeses and suggest potential for developing origin designation policies founded on microbiological insights.
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- In low-income countries, photometers like HemoCue-301 are used to screen and manage anaemia and assess iron status for public health interventions.
- This study evaluated the accuracy of HemoCue-301 in determining haemoglobin levels in anaemic children aged 6-12 months in rural Africa, using a more precise reference method, Sysmex XN-1500.
- Results showed significant bias in HemoCue-301 measurements for children with haemoglobin below 8.0g/dL, indicating it may not reliably measure low haemoglobin levels in this population.
Unlabelled: Oncology therapies have repercussions on the quality of life of patients. This quality of life is a cardinal element in the care pathway of patients. We initiated this work to assess the quality of life after mastectomy.
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