Publications by authors named "A Camacho-Ortiz"
Background: Antimicrobial resistance and difficult-to-treat resistance (DTR) in ESKAPE pathogens ( and species) is a threat to human health. The aim of this study was to determine the prevalence of antimicrobial resistance and DTR rates in ESKAPE pathogens over six years in a third-level hospital from Monterrey, Mexico.
Methods: Antimicrobial susceptibility testing was determined by either disk diffusion or broth microdilution in strains from 2018 to 2023.
Objective: Outpatient antimicrobial therapy works but often requires in-person oversight. Advancements enable seamless communication. We used instant messaging to track adherence, cost, efficacy, and adverse events for outpatient intramuscular antibiotic therapy.
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- The study investigates the effectiveness of various antimicrobial combinations against multidrug-resistant (MDR) and extensive drug-resistant (XDR) strains of a prominent nosocomial pathogen that poses a significant public health threat.
- Researchers assessed the genetic characteristics of 100 isolates, noting high prevalence of drug resistance genes and variations in expression of efflux pumps and porins, indicating complex resistance mechanisms.
- Two promising combinations, levofloxacin-ampicillin/sulbactam and meropenem-colistin, showed synergistic effects in inhibiting bacterial growth, but differing results across testing methods suggest further research is required to optimize treatment strategies.
Multicenter study on infections in Mexico: exploring the landscape.
Infect Control Hosp Epidemiol
October 2024
Article Synopsis
- - The study examined Clostridioides difficile infection (CDI) trends and outcomes in 16 healthcare facilities in Mexico from 2016 to 2022, focusing on patient demographics and clinical data.
- - Out of 2,356 CDI cases identified, 90% were healthcare-associated, with common comorbidities including hypertension and diabetes; the 30-day mortality rate was 16%.
- - The findings highlight the need for improved surveillance and standardized CDI classification in Mexico, noting stable rates but differences in incidence between public and private hospitals.
MALDI-TOF MS profiling to predict resistance or biofilm production in gram-positive ESKAPE pathogens from healthcare-associated infections.
Diagn Microbiol Infect Dis
January 2025
Antimicrobial resistance and biofilm production in healthcare-associated infections is a health issue worldwide. This study aimed to identify potential biomarker peaks for resistance or biofilm production in ESKAPE pathogens using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Antimicrobial susceptibility and biofilm production were assessed on selected isolates.
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