Decreased pancreatic bicarbonate secretion may be responsible for the low duodenal pH in chronic pancreatitis as compared to the normal. We have therefore performed a 24-hour continuous duodenal pH recording in 7 patients with chronic pancreatitis and in 7 controls. The comparison of results, expressed as the percent of the time with pH under 3, 4, 5 or 6, shows that in chronic pancreatitis, the duodenal pH was significantly lower than in normal subjects, particularly during the postprandial periods.
View Article and Find Full Text PDFWe report a case of a 56 year old woman who presented with a long history of chronic attacks of vomiting. On admission to hospital she was cachectic, and attempted parenteral nutrition induced coma. The illness was found to be due to citrullinaemia, a metabolic disorder of the urea cycle.
View Article and Find Full Text PDFWe report the case of a 56-year-old woman with a history of episodes of vomiting and coma. Hyperammoniemia , hypouremia , hypercitrullinemia and the decreased arginino -succinic synthetase activity on skin fibroblast cultures permitted us to diagnose citrullinemia. We think that the skin changes, i.
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