Effect of acyclovir on the replication of turkey herpesvirus and Marek's disease virus.

The toxicity of acyclovir for chick embryo fibroblasts and its effect on the replication of turkey herpesvirus (strain FC 126) and Marek's disease virus (strain HPRS 16) multiplied on fibroblast culture was studied. The influence of using acyclovir on the development of the tumour process in birds infected with a virulent Marek's disease virus was also determined. Acyclovir used in doses below 12.

Effect of a preliminary infection of ducks with EDS-76 virus on the Derzsy's disease pathology.

The aim of this work was to investigate the role of a non pathogenic adenovirus (EDS-76, strain A-127), frequently isolated from ducklings on the infection by a pathogen agent (such as the parvovirus responsible for Derzsy's disease, DDV). Three groups of ducklings were respectively infected with A-127 alone, at day old, DDV alone at day 10th, A-127 at day old plus DDV at day 10th. The infected groups and a control one were raised under similar conditions.