Publications by authors named "A Cabau"
Objective: Prenatal exposure to diethylstilbestrol (DES) is associated with adverse effects, including genital anomalies and cancers in men and women. Animal studies showed birth defects and tumors in the offspring of mice prenatally exposed to DES. In humans, birth defects, such as hypospadias were observed in children of prenatally exposed women.
View Article and Find Full Text PDFObjective: Exposure to diethylstilbestrol (DES) in utero is associated with adverse health effects, including genital anomalies in women and men, and cancers in women. Animal studies showed birth defects and tumors in the offspring of DES exposed mice, revealing transgenerational transmission of DES effects. In humans, birth defects, such as hypospadias were observed in children of prenatally exposed women.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to assess the cancer risk, particularly breast cancer, among women in France who were exposed to diethylstilbestrol (DES) before birth.
- A total of 3,436 women exposed to DES were compared to 3,256 unexposed women, with cancer cases confirmed through medical history.
- Results showed a significant increase in breast cancer among the exposed group, with a multivariate incidence rate ratio of 2.10, indicating more than double the risk compared to unexposed women.