Supporting long-term condition management: a workflow framework for the co-development and operationalization of machine learning models using electronic health record data insights.

The prevalence of long-term conditions such as cardiovascular disease, chronic obstructive pulmonary disease (COPD), asthma, and diabetes mellitus is rising. These conditions are leading sources of premature mortality, hospital admission, and healthcare expenditure. Machine learning approaches to improve the management of these conditions have been widely explored, with data-driven insights demonstrating the potential to support earlier diagnosis, triage, and treatment selection.

Development, validation and application of a high-performance liquid chromatography method for the detection of ibuprofen in elephant plasma.

A simple and accurate method for the determination of ibuprofen concentrations in elephant plasma was developed and validated using reverse phase high-performance liquid chromatography (HPLC). Utilizing a liquid-liquid extraction with ethyl acetate, methanol, and phosphoric acid, samples were separated on an XBridge C column. The mobile phase consisted of 0.

IMMOBILIZATION OF BLACK HOWLER MONKEYS () USING BUTORPHANOL, AZAPERONE, MEDETOMIDINE IS SAFE AND EFFECTIVE FOR NONINVASIVE PROCEDURES.

Administration of butorphanol, azaperone, and medetomidine (BAM) for immobilization of black howler monkeys () has not been previously reported. In this observational study, 0.02 ml/kg of compounded BAM (butorphanol 27.