Publications by authors named "A CHAVY"
Changes in biodiversity may impact infectious disease transmission through multiple mechanisms. We explored the impact of biodiversity changes on the transmission of Amazonian leishmaniases, a group of wild zoonoses transmitted by phlebotomine sand flies (Psychodidae), which represent an important health burden in a region where biodiversity is both rich and threatened. Using molecular analyses of sand fly pools and blood-fed dipterans, we characterized the disease system in forest sites in French Guiana undergoing different levels of human-induced disturbance.
View Article and Find Full Text PDFFrench Guiana is a European ultraperipheric region located on the northern Atlantic coast of South America. It constitutes an important forested region for biological conservation in the Neotropics. Although very sparsely populated, with its inhabitants mainly concentrated on the Atlantic coastal strip and along the two main rivers, it is marked by the presence and development of old and new epidemic disease outbreaks, both research and health priorities.
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- A key challenge in eco-epidemiology is understanding the factors that influence infectious disease transmission and creating risk maps for public health use.
- The study utilizes ecological niche modelling and human cases of cutaneous leishmaniasis (CL) to predict disease risk based on environmental, climatic, and anthropogenic variables in the Amazon and French Guiana.
- Findings indicate that areas with significant human impact are primarily at risk for CL, underscoring the importance of human activity in assessing disease risks despite CL's association with natural cycles in the region.
Article Synopsis
- Phlebotomine sand flies are key vectors of leishmaniasis, making their accurate identification crucial for studying the disease.
- Traditional methods for identifying these flies are slow and complex, while molecular techniques can be costly.
- Recent research validates the use of MALDI-TOF MS as an efficient and affordable method for identifying Northern Amazonian sand flies, resulting in successful species identification in blind tests.
Esophageal prothesis (EP) is a palliative treatment for inoperable neoplastic stenosis. Ninety-one patients were candidates for EP placement between 1978 and 1983. EP placement was successful in 77 patients.
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