Publications by authors named "A C van Gemert"
Impact of COVID-19 social distancing measures on lung transplant recipients: decline in overall respiratory virus infections is associated with stabilisation of lung function.
Eur Respir J
November 2022
Article Synopsis
- COVID-19 social distancing measures led to a notable drop in non-COVID-19 respiratory virus infections, allowing for an analysis of their effects on lung function in lung transplant recipients (LTRs) between 2009 and 2020.* -
- Data from 479 LTRs showed a significant difference in annual FEV decline, where it remained stable during social distancing (5 mL) compared to a decline pre-social distancing (-114 mL), with frequent bouts of temporary drops in lung function (TDLF) associated with faster FEV declines.* -
- The study found lower rates of TDLF and chronic lung allograft dysfunction (CLAD) during social distancing, suggesting that reduced respiratory virus circulation
Introduction: Evidence on physical and psychological well-being of in-hospital cardiac arrest (IHCA) survivors is scarce. The aim of this study is to describe long-term health-related quality of life (HRQoL), functional independence and psychological distress 3 and 12 months post-IHCA.
Methods: A multicenter prospective cohort study in 25 hospitals between January 2017 - May 2018.
In some myopathies, hypoxia can be the result of pathologic effects like muscle necrosis and abnormal blood flow. At the molecular level, the consequence of hypoxic conditions is not yet fully understood. Under stress conditions, many housekeeping gene mRNAs are translationally silenced, while translation of other mRNAs increases.
View Article and Find Full Text PDFBackground: In skeletal muscle each muscle cell, commonly called myofiber, is actually a large syncytium containing numerous nuclei. Experiments in fixed myofibers show that mRNAs remain localized around the nuclei in which they are produced.
Methodology/principal Findings: In this study we generated transgenic flies that allowed us to investigate the movement of mRNAs in body wall myofibers of living Drosophila embryos.
The genes involved in flagellum synthesis, motility and chemotaxis in Escherichia coli are expressed in a hierarchical fashion. At the top of the hierarchy lies the master regulator FlhDC, required for the expression of the whole set of genes. The operon flhDC is controlled by numerous regulators including H-NS, CRP, EnvZ/OmpR, QseBC and LrhA.
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