Publications by authors named "A C Van Steirteghem"
This monograph, written by the pioneers of IVF and reproductive medicine, celebrates the history, achievements, and medical advancements made over the last 40 years in this rapidly growing field.
View Article and Find Full Text PDFObjective: To present an overview of the numbers and types of human embryos used in research projects in Belgium from 2007 to 2015.
Design: Analysis of all research proposals approved by the Federal Commission for Medical and Scientific Research on Embryos In Vitro.
Setting: Not applicable.
Study Question: Are reproductive hormone levels (FSH, LH, inhibin B and testosterone) in male offspring conceived by ICSI because of male infertility comparable with those from peers born after spontaneous conception?
Summary Answer: In this cohort of 54 young men conceived by ICSI because of male-factor infertility, mean and median reproductive hormone levels were found to be comparable with results from spontaneously conceived peers, but ICSI-conceived men were more likely to have low inhibin B (<10th percentile) and high FSH (>90th percentile) levels.
What Is Known Already: Since the worldwide oldest ICSI offspring have recently reached young adulthood, their reproductive health can now be investigated. This typically involves semen analysis and a hormonal profiling including the measurement of FSH, LH, inhibin B and testosterone.
Study Question: What is the semen quality of young adult men who were conceived 18-22 years ago by ICSI for male infertility?
Summary Answer: In this cohort of 54 young adult ICSI men, median sperm concentration, total sperm count and total motile sperm count were significantly lower than in spontaneously conceived peers.
What Is Known Already: The oldest ICSI offspring cohort worldwide has recently reached adulthood. Hence, their reproductive health can now be investigated.