ReLink strategy in diagnosed-but-untreated hepatitis C-positive patients in Germany: report from a single center.

Objective: The ReLink project aims to reintegrate diagnosed-but-untreated hepatitis-C-positive patients into medical care and initiate a therapy.

Material/methods: A retrospective search within the practice management system of a single center in Germany identified among 1965 hepatitis-C-positive patients 100 untreated patients with available contact details and meeting all inclusion criteria. Patients were contacted by 2 contact rounds.

Resource-based trade-offs and the adaptive significance of seasonal plasticity in butterfly wing melanism.

Phenotypic plasticity is the ability of an organism to alter its phenotype in response to environmental cues. This can be adaptive if the cues are reliable predictors of impending conditions and the alterations enhance the organism's ability to capitalize on those conditions. However, since traits do not exist in isolation but as part of larger interdependent systems of traits (phenotypic integration), trade-offs between correlated plastic traits can make phenotypic plasticity non- or maladaptive.

Voice onset time and vowel formant measures in online testing and laboratory-based testing with(out) surgical face masks.

Since the COVID-19 pandemic started, conducting experiments online is increasingly common, and face masks are often used in everyday life. It remains unclear whether phonetic detail in speech production is captured adequately when speech is recorded in internet-based experiments or in experiments conducted with face masks. We tested 55 Spanish-Basque-English trilinguals in picture naming tasks in three conditions: online, laboratory-based with surgical face masks, and laboratory-based without face masks (control).

One-to-One or One ? Linking Sound-to-Letter Mappings to Speech Sound Perception and Production in Early Readers.

Purpose: Effects related to literacy acquisition have been observed at different levels of speech processing. This study investigated the link between orthographic knowledge and children's perception and production of specific speech sounds.

Method: Sixty Spanish-speaking second graders, differing in their phonological decoding skills, completed a speech perception and a production task.

Real-World Safety, Effectiveness, and Patient-Reported Outcomes in Patients with Chronic Hepatitis C Virus Infection Treated with Glecaprevir/Pibrentasvir: Updated Data from the German Hepatitis C-Registry (DHC-R).

Using data from the German Hepatitis C-Registry (Deutsche Hepatitis C-Register, DHC-R), we report the real-world safety and effectiveness of glecaprevir/pibrentasvir (GLE/PIB) treatment and its impact on patient-reported outcomes (PROs) in underserved populations who are not typically included in clinical trials, yet who will be crucial for achieving hepatitis C virus (HCV) elimination. The DHC-R is an ongoing, non-interventional, multicenter, prospective, observational cohort study on patients treated for chronic HCV infection in Germany. The data cutoff was 17 January 2021.