Publications by authors named "A C Rigby"
Thorium-227 (Th) is an α-emitting radionuclide currently under investigation for targeted alpha therapy. Available chelators used for this isotope suffer from challenging multistep syntheses. Here, we present the synthesis and preclinical evaluation of a novel bifunctional chelator, SCN-Bn-DOTHOPO, which contains an isothiocyanate group that is suitable for conjugation to biological molecules.
View Article and Find Full Text PDFAims: This pilot randomised controlled trial aimed to evaluate the effect of introducing isCGM on glycaemic control and diabetes distress in individuals with T2DM receiving non-insulin therapies.
Materials And Methods: Forty adults with T2DM were randomised to either receive FreeStyle Libre 2 (Libre 2), an isCGM system, or FreeStyle Libre Pro iQ (Libre Pro) also known as 'blinded' CGM. Participants were followed for 12 weeks.
Article Synopsis
- Ovarian torsion (OT) is a rare but critical gynecological emergency that requires quick diagnosis and management, leading researchers to explore non-invasive biomarkers for detection.
- A systematic review of literature from five databases examined studies on biomarkers related to OT, resulting in the inclusion of 23 articles that reported on both animal and human research.
- Key biomarkers identified included ischemia-modified albumin (IMA), serum D-dimer (s-DD), and interleukin-6 (IL-6), with specificities reaching 93.3% and sensitivities ranging from 16.4% to 92.3%, indicating their potential for early identification of OT in patients.