Publications by authors named "A C Ricard"

Introduction: In order to find early selection criteria to improve the longevity of show jumping horses, a specific protocol was designed.

Methods: Before entering competition, young horses selected from extreme stallions for longevity were measured for many traits, including blood parameters. Blood samples were taken from 952 horses aged 2-4 years old, sired by two groups of stallions: one with unfavorable (U) and the other with favorable (F) extreme estimated breeding values for functional longevity.

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Objective: To study the impact of nonpharmaceutical interventions implemented during the COVID-19 pandemic on the monthly incidence of sudden unexpected death in infancy (SUDI) cases overall and those with a viral or bacterial identification.

Study Design: We conducted an interrupted time-series analysis using seasonally adjusted Poisson regression models from the French national prospective and multicenter SUDI registry, that included all SUDI cases below the age of 1 year who died from 2016 to 2021 in mainland France.

Results: Of 998 SUDI cases analyzed, 750 were recorded during the prepandemic period (January 2016 through March 2020) and 248 during the NPI period (April 2020 through December 2021).

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Article Synopsis
  • The Franches-Montagnes (FM) is Switzerland's last native horse breed, created in the 19th century through cross-breeding local mares and Anglo-Norman stallions, with a study analyzing genetic data from 522 FM horses and various other breeds to explore population structure and genetic diversity.
  • A three-step approach revealed distinct population substructures within the FM breed linked to genetic origins and influential sires, with admixture from Thoroughbreds being prominent and decreased genetic variance associated with older-type horses.
  • The study showed FM horses have lower inbreeding levels compared to other breeds, but some long segments of homozygosity indicate a potential loss of genetic diversity, with specific genes linked to desirable traits in breeding
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The E3 ubiquitin ligase thyroid hormone receptor interacting protein 12 (TRIP12) has been implicated in pancreatic adenocarcinoma (PDAC) through its role in mediating the degradation of pancreas transcription factor 1a (PTF1a). PTF1a is a transcription factor essential for the acinar differentiation state that is notably diminished during the early steps of pancreatic carcinogenesis. Despite these findings, the direct involvement of TRIP12 in the onset of pancreatic cancer has yet to be established.

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Article Synopsis
  • * Current research involved analyzing genetic data from multiple horse breeds to investigate the population structure of the Einsiedler horse, but it proved challenging to distinguish it from other European Warmbloods.
  • * However, the study identified unique genetic markers, or "runs of homozygosity," specific to the Einsiedler horse, suggesting that future breeding should focus on these genetic traits and consider using stored genetic material from selected stallions.
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