Publications by authors named "A C Pomeroy"
The influence of transcatheter aortic valve replacement on left atrial mechanics: a systematic review and meta-analysis.
Eur Heart J Imaging Methods Pract
April 2024
Aims: The morphology and function of the left atrium (LA) are intimately tied to left ventricular loading conditions. Data pertaining to the effect of transcatheter aortic valve replacement (TAVR) on LA function and geometry are scarce. The aim of the study was to quantify associations between TAVR and LA remodelling by pooling available data from published observational studies.
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- Most aggressive lymphomas are usually treated with combination chemotherapy, like the "CHOP" regimen, which is believed to be optimal when drugs work well together (synergy).
- Research on PTCL cell lines shows that the CHOP regimen often exhibits antagonistic interactions rather than synergy, leading to questions about how to improve treatment effectiveness.
- Surprisingly, concurrent administration of these drugs still leads to maximum tumor cell kill, and this can be explained using the linear-quadratic model from radiology, suggesting that even with negative interactions, the way drugs are given can result in better clinical outcomes.
Purpose: To investigate whether venous blood pooling in the lower limbs from prolonged sitting induces harmful cardiovascular effects by reducing stroke volume (SV) and cardiac output (CO).
Methods: A randomized crossover trial involving 16 participants (mean age = 24.8 years ± 6.
Article Synopsis
- Living shorelines are designed to protect coastlines from hazards while offering additional benefits like carbon sequestration, but their use in Australia remains limited.
- A survey and literature review identified 138 living shoreline projects in Australia, with over half deemed successful in reducing hazard risk since 2000.
- Despite limited peer-reviewed evidence, there is a growing interest and practical implementation of living shorelines across Australia, highlighting a need for better information sharing among practitioners.
Unlabelled: Combination therapy is an important part of cancer treatment and is often employed to overcome or prevent drug resistance. Preclinical screening strategies often prioritize synergistic drug combinations; however, studies of antibiotic combinations show that synergistic drug interactions can accelerate the emergence of resistance because resistance to one drug depletes the effect of both. In this study, we aimed to determine whether synergy drives the development of resistance in cancer cell lines using live-cell imaging.
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