Publications by authors named "A C Piscaglia"
Article Synopsis
- Mucosal healing (MH) is the primary goal in treating ulcerative colitis (UC), but some patients still experience relapses despite achieving MH.
- A study analyzed UC patients who reached MH, discovering that histologic activity (HA) beyond MH might explain these relapses and found specific lesions that increase relapse risk.
- Key findings showed that higher baseline histological lesions, particularly basal plasmacytosis and surface irregularity, are significant risk factors for relapse, indicating that HA remains an important concern even with MH.
Strongyloides stercoralis is a neglected parasite that can cause death in immunocompromised individuals. There were no data on the epidemiology of S. stercoralis infection in San Marino Republic until two patients (one of whom died) were diagnosed with severe strongyloidiasis (hyperinfection) between September 2016 and March 2017.
View Article and Find Full Text PDFBackground: The burden of Crohn's disease (CD) and ulcerative colitis (UC) has never been estimated in the Republic of San Marino, the third smallest nation of the world.
Aims: To assess the occurrence and clinical features of CD and UC in San Marino during the last 35 years.
Methods: We retrospectively evaluated the prevalence, incidence, and main clinical aspects of CD and UC from 1980 to 2014, crossing data from various sources.
Aim: To evaluate if a single and/or combined (clinical, endoscopic and radiological) assessment could predict clinical outcomes in Crohn's disease (CD).
Methods: We prospectively evaluated 57 CD cases who underwent both a colonoscopy and a CT-enterography (CTE). Harvey-Bradshaw Index (HBi), SES-CD (and/or Rutgeerts score) and the radiological disease activity were defined to stratify patients according to clinical, endoscopic and radiological disease activity respectively.
Aim: To evaluate the prevalence of nodular lymphoid hyperplasia (NLH) in adult patients undergoing colonoscopy and its association with known diseases.
Methods: We selected all cases showing NLH at colonoscopy in a three-year timeframe, and stratified them into symptomatic patients with irritable bowel syndrome (IBS)-type symptoms or suspected inflammatory bowel disease (IBD), and asymptomatic individuals undergoing endoscopy for colorectal cancer screening. Data collection included medical history and final diagnosis.