Publications by authors named "A C Perez de Diego"
Paclitaxel (PTX) is a commonly used chemotherapeutic drug, however, one of its major adverse effects is chronic neuropathic pain, with the incidence being higher in women than in men. The neurobiological mechanisms behind this sex difference are still largely unclear, and the endocannabinoid system, which exhibits sexual dimorphism and plays a key role in pain regulation, is a promising area for further studies. The present study aimed to characterise pain-, cognition-, anxiety-, and depression-related behaviours in male and female rats following PTX administration, and associated alterations in the endocannabinoid system.
View Article and Find Full Text PDFErratum to 'Cough severity visual analog scale scores and quality of life in patients with refractory or unexplained chronic cough' [Respir Investig 62(6) (2024), 987-994].
Respir Investig
January 2025
Article Synopsis
- This study investigates how the severity of chronic cough affects the quality of life (QoL) and other outcomes for Spanish patients with refractory chronic cough (RCC) or unexplained chronic cough (UCC).
- Patients self-reported cough severity using various tools, and their results were categorized into three groups based on cough severity scores, revealing a direct link between higher severity and worse QoL.
- The findings suggest that patients with more severe coughs reported greater negative impacts on their daily lives, indicating they may need more targeted treatment interventions.
Background: Metabolic syndrome (MetS) is a cluster of medical conditions and risk factors correlating with insulin resistance that increase the risk of developing cardiometabolic health problems. The specific criteria for diagnosing MetS vary among different medical organizations but are typically based on the evaluation of abdominal obesity, high blood pressure, hyperglycemia, and dyslipidemia. A unique, quantitative and independent estimation of the risk of MetS based only on quantitative biomarkers is highly desirable for the comparison between patients and to study the individual progression of the disease in a quantitative manner.
View Article and Find Full Text PDFPurpose: The purpose of this study was to validate the performance of a portable and remotely controlled slit lamp imaging adaptor.
Methods: Twenty patients with anterior eye segment conditions participated in a randomized masked clinical trial. Imaging was performed using a Haag-Streit AG, BX 900 slit lamp biomicroscope and a new slit lamp prototype.