Publications by authors named "A C Niles"

Article Synopsis
  • This study examines the risk factors for Alzheimer disease patients who also experience neuropsychiatric symptoms (ADNPS) in both males and females.
  • Researchers analyzed data from a regional Alzheimer care center using univariate analysis and logistic regression to identify these risk factors.
  • Findings indicate that male ADNPS patients are linked to dyslipidemia and cerebral infarction, while female ADNPS patients have a stronger association with chronic heart failure.
View Article and Find Full Text PDF
Article Synopsis
  • - A significant number of individuals exposed to combat-related trauma develop PTSD, which negatively affects their mental and physical health, highlighting the need for new treatment methods.
  • - This pilot study tested a new computer-based intervention using "affect labeling" on veterans with PTSD, revealing that those who underwent the intervention showed reduced PTSD symptoms and decreased brain reactivity to trauma cues.
  • - Results indicate that affect labeling might be an effective and low-cost option for treating PTSD, suggesting avenues for future research and development in this area.
View Article and Find Full Text PDF

Introduction: This study aimed to examine baseline risk factors in Alzheimer's Disease (AD) and Vascular dementia (VaD) patients with neuropsychiatry symptoms (NPS), and determine whether specific risk factors differ by subtypes of dementia for AD and VaD patients with NPS.

Methods: A retrospective data analysis was conducted to evaluate similarities and differences in the risk factors for AD and VaD with NPS. The analysis included 2949 patients with VaD and 6341 patients with clinical confirmation of AD and VaD with or without NPS collected between February 2016 and August 2021.

View Article and Find Full Text PDF

This chapter describes a simple, nondestructive, annexin V apoptosis detection method that can be employed in real time over a 48-h test exposure. The real-time functionality allows for temporal resolution of apoptotic and cell death responses during the test exposure and obviates the need for onerous sample preparation and time course protocols associated with other annexin V methods. Further, this technique is eminently accessible to a wide range of laboratories because it does not require flow cytometry or other cytometric methods.

View Article and Find Full Text PDF