Prevalence and clinical determinants of low bone mineral density in anorexia nervosa.

Objective: To determine the prevalence of low bone mass in anorexia nervosa (AN) and the association with clinical parameters.

Methods: A cross-sectional study on 286 Caucasian women with AN. Bone mineral density (BMD) was measured with DXA.

Bone turnover and hip bone mineral density in patients with sarcoidosis.

Background And Aim Of The Work: Sarcoidosis is a chronic inflammatory T-cell-driven disease that can also affect bone. We evaluated bone remodelling and bone mineral density (BMD) in patients with sarcoidosis and their dependency of disease-related and treatment-related factors.

Methods: In 124 patients BMD of the hip (DXA) and markers of bone resorption (ICTP) and formation (PINP) were evaluated.

Polymorbidity in diabetes in older people: consequences for care and vocational training.

Objective: To investigate the prevalence of complicating and concurrent morbidities in older diabetic patients and to evaluate to what extent their occurrence affects the burden of disease and use of medical healthcare.

Study Design: Cross-sectional analysis of retrospectively obtained data on comorbidities and use of medical healthcare. Healthcare registration systems were used to retrieve data on 300 patients with diabetes aged >or=60 years who, according to the severity of their disease and intensity of care required, were treated in a regional general practitioner (GP), diabetes nurse specialist (DNS) or medical specialist (MS) practice.

Co-ingestion of leucine with protein does not further augment post-exercise muscle protein synthesis rates in elderly men.

Leucine has been suggested to have the potential to modulate muscle protein metabolism by increasing muscle protein synthesis. The objective of this study was to investigate the surplus value of the co-ingestion of free leucine with protein hydrolysate and carbohydrate following physical activity in elderly men. Eight elderly men (mean age 73 +/- 1 years) were randomly assigned to two cross-over treatments consuming either carbohydrate and protein hydrolysate (CHO+PRO) or carbohydrate, protein hydrolysate with additional leucine (CHO+PRO+leu) after performing 30 min of standardized physical activity.