Publications by authors named "A C Minguez"
Leishmaniasis in Patients With Inflammatory Bowel Disease: A National Multicenter Study of GETECCU.
United European Gastroenterol J
January 2025
Background: Leishmaniasis (LI) is a vector-borne illness caused by a protozoan of the genus Leishmania. Data on the features of LI in patients with inflammatory bowel disease (IBD) are scarce.
Aim: To describe the characteristics of patients with IBD who present with leishmaniasis, infection outcomes and the risk factors associated with developing visceral leishmaniasis (VL).
Background And Aims: Ustekinumab is an effective treatment for inflammatory bowel diseases. However, some patients do not respond to conventional doses. The aim of the study was to evaluate the effectiveness of intravenous maintenance ustekinumab in patients with secondary failure.
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- Inflammatory bowel disease (IBD) is a chronic intestinal disorder, including Crohn's disease and ulcerative colitis, characterized by symptoms like diarrhea, rectal bleeding, and abdominal pain, with serious potential complications.
- Current therapies, especially biologics that target specific proteins, can struggle due to varying patient responses, leading to treatment failures and the need for personalized approaches.
- Pharmacogenetics can help improve treatment by identifying genetic variants (SNPs) linked to drug response, with the review focusing on SNPs related to immune function and their role in predicting responses to biologic therapies for IBD.
Background And Aims: Recent studies point out to epidemiological changes in primary sclerosing cholangitis (PSC). Our aims were to determine in PSC patients followed in several centers in a Mediterranean geographic area: (i) changes in baseline features and (ii) effect of gender on clinical course.
Methods: Retrospective multicenter study of PSC patients treated in 8 hospitals in a Mediterranean area between 2000 and 2021.
Background: The usefulness of thiopurines has been poorly explored in pouchitis and other pouch disorders.
Objective: To evaluate the effectiveness and safety of azathioprine as maintenance therapy in inflammatory pouch disorders.
Design: This was a retrospective and multicentre study.