Clinical and immunological features of specific antibody deficiency in a pediatric hospital in Colombia.

Introduction. Specific antibody deficiency is an innate error of humoral immunity characterized by normal levels of immunoglobulin isotypes, recurrent infections, and a reduced reaction to polysaccharide antigens in vaccines. Objective.

Shallow groove technique in sextant pattern femtosecond laser-assisted cataract surgery.

Femtosecond laser-assisted cataract surgery (FLACS) is a useful technology for anterior segment surgery that creates cleavage planes via photodisruption of ocular tissue. Compared to conventional cataract surgery, FLACS has been thought to potentially improve surgical precision, accuracy, and reproducibility. Its introduction into cataract surgery has enabled the development of new techniques and has been purported to be potentially beneficial in improving surgical safety and providing quicker visual rehabilitation.

Protein-polyelectrolyte complexation: effects of sterically repulsive groups, macromolecular architecture and hierarchical assembly.

Self-assembly of proteins and polyelectrolytes in aqueous solutions is a promising approach for the development of advanced biotherapeutics and engineering efficient biotechnological processes. Synthetic polyions containing sterically repulsive ethylene oxide moieties are especially attractive as protein modifying agents, as they can potentially induce a PEGylation-like stabilizing effect without the need for complex covalent binding reactions. In this study, we investigated the protein-binding properties of anionic polyelectrolytes based on an inorganic polyphosphazene backbone, with ethylene oxide groups incorporated into both grafted and linear macromolecular topologies.

Biochemical and histological effects of the subchronic treatment with a beer containing Baccharis dracunculifolia in an experimental model of diabetes.

This article reports the development of a beer made with Baccharis dracunculifolia and its application in an experimental model of diabetes. Initially, the production of the beverage was standardized in order to incorporate the plant extract properly. Next, the beer was analyzed by the UHPLC-MS to identify the substances present.