Publications by authors named "A C Lorusso"
Background: Primary Immunodeficiency disorders (PID) can increase the risk of severe COVID-19 and prolonged infection. This study investigates the duration of SARS-CoV-2 excretion and the genetic evolution of the virus in pediatric PID patients as compared to immunocompetent (IC) patients.
Materials And Methods: A total of 40 nasopharyngeal and 24 stool samples were obtained from five PID and ten IC children.
Biting midges ( spp.) are important vectors of several insect borne arboviruses but are underrepresented in terms of availability of high-resolution genomic resources. We assembled and annotated complete mitochondrial genomes for two species, namely and which are proven vectors for Bluetongue Virus (BTV).
View Article and Find Full Text PDFThe virus species Protoparvovirus carnivoran 1 encompasses pathogens that infect both domestic and wild carnivores, including feline panleukopenia virus. We identified and characterized feline panleukopenia virus strains in a Marsican brown bear (Ursus arctos marsicanus) and a crested porcupine (Hystrix cristata) in Italy, extending the known host range of this virus.
View Article and Find Full Text PDFArticle Synopsis
- Bluetongue virus (BTV) and epizootic haemorrhagic disease virus (EHDV) are viruses spread by biting midges that cause serious diseases in ruminants, and they circulate in different forms (serotypes).
- A new EHDV strain (serotype 8) was first found in Tunisia in 2021 and later identified in cattle in Italy, Spain, Portugal, and France in 2022, where BTV is already a concern.
- Researchers developed a TaqMan RT-qPCR assay that efficiently detects and differentiates BTV and EHDV, providing a quick and cost-effective method for diagnosis, aiding in better surveillance and control of these diseases.
Article Synopsis
- - Bluetongue (BT) and Epizootic Hemorrhagic Disease (EHD) are important animal diseases impacting cattle and sheep, caused by viruses transmitted by biting midges, with recent outbreaks noted in France during the summer of 2023.
- - Genomic analysis revealed three viruses involved in the outbreaks: EHDV-8, which matches strains found in southern Europe since 2021, and two different strains of BTV, including a novel BTV-8 strain and an established BTV-4 strain.
- - The 2023 outbreaks indicate unusual dynamics in the circulation and emergence of these viruses in France, prompting further investigation into the epidemiological factors contributing to their spread.