Publications by authors named "A C Januel"
Background: While advances in endovascular thrombectomy (EVT) have led to high reperfusion rates, most patients treated with EVT do not avoid disability. Post-reperfusion hemorrhagic transformation (HT) is a potential target for improving outcomes. This study examined pretreatment blood-brain barrier (BBB) disruption in tissue that would subsequently become part of the final infarct to evaluate its role in post-EVT HT.
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- Mechanical thrombectomy (MT) has significantly improved outcomes for acute ischemic stroke, but the challenge lies in ensuring widespread access and sufficient training for interventional neuroradiologists (INRs) across Europe.
- A survey conducted among European Society of Minimally Invasive Neurological Therapy (ESMINT) members collected responses from 240 INRs across 33 countries, revealing that many thrombectomy-capable stroke centers perform fewer than 150 MT procedures yearly and mostly use specific techniques for recanalization.
- The findings highlight a disparity in MT practices among centers and suggest a need for more staffing and training programs to meet the increasing demand for MT in Europe.
Article Synopsis
- The study aimed to track the outcomes of patients with brain arteriovenous malformations (AVMs) who were managed conservatively, revealing key statistics on related morbidity and mortality over a 10-year period.
- Out of 1010 patients initially recruited, 434 were analyzed, with a majority having unruptured low-grade AVMs, demonstrating a 5% occurrence of serious outcomes and a higher risk in those with a history of rupture or older age.
- During the follow-up of approximately 3.2 years, 8% of patients experienced major intracranial hemorrhages, highlighting the ongoing risks associated with conservative management of AVMs.
Background: The Woven EndoBridge (WEB) device is designed to treat wide-necked bifurcation aneurysms. The WEB 17 is the latest iteration and can be delivered through a 0.017″ microcatheter.
View Article and Find Full Text PDFBackground: Electrochemical impedance spectroscopy can determine characteristics such as cell density, size, and shape. The development of an electrical impedance-based medical device to estimate acute ischemic stroke (AIS) clot characteristics could improve stroke patient outcomes by informing clinical decision making.
Objectives: To assess how well electrical impedance combined with machine learning identified red blood cell (RBC)-rich composition of AIS clots , which is associated with a successfully modified first-pass effect.